Linked Programmes

Overview of SCIMITAR-SA

Tobacco dependence is a chronic relapsing condition and a precursor to several MLTCs. In people with severe mental illness (SMI), tobacco use exacerbates health inequalities and reduces life expectancy. Efforts for tobacco cessation are critical in addressing MLTCs in SMI populations, particularly in low-resource settings like South Asia, which have a high burden of tobacco-related morbidity and mortality.

SCIMITAR-SA Research Question: Can we treat tobacco dependence among individuals in South Asia with the most severe forms of mental illnesses, in order to prevent the onset and progression of tobacco-related multiple-long term conditions (MLTCs)?

The project will have 4 work packages: (1) Adaptation, (2) Feasibility and Trial, (3) Health Economics, and (4) Implementation Science, and will also build local capacity in tobacco cessation and applied research in mental and physical multimorbidity.

Throughout the course of the project, the teams will conduct a review of existing interventions for tobacco cessation in South Asia, production of the SCIMITAR-SA intervention package, and hold stakeholder workshops; then the commencement of first a pilot trial, and full trial. An economic evaluation will identify the cost-effectiveness of SCIMITAR-SA as well as its distributional health impacts from a health systems perspective.

SCIMITAR-SA has promising prospects of clinical and cost-effectiveness, and the project will ensure its sustainability through clinical capacity building and identifying appropriate methods for the wider implementation of the intervention package in South Asia.

Through stakeholder engagement, the project teams will ensure knowledge translation into practice and policy, and enhance capacity in South Asia for applied health research on MLTCs

This research is funded by the NIHR (NIHR205601) using UK aid from the UK Government to support global health research. The views expressed on this website are those of the author(s) and not necessarily those of the NIHR or the UK government.